Anti-Topoisomerase II alpha/TOP2A Antibody

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Anti-Topoisomerase II Antibody, clone KiS1 is a Mouse Monoclonal Antibody for detection of Topoisomerase II also known as Ki-S1 & has been validated in FC, WB, ICC, IHC, IHC(P). - Find MSDS or SDS, a COA, data sheets and more information. Anti-topoisomerase antibodies (ATA) are autoantibodies directed against topoisomerase and found in several diseases, most importantly scleroderma. Diseases with ATA are autoimmune disease because they react with self-proteins. They are also referred to as anti-DNA topoisomerase I antibody (anti-topo At SRUK Annual Conference 2017 anti-Topoisomerase II antibody [SQab1727] is a Recombinant Rabbit Monoclonal antibody [SQab1727] recognizes Topoisomerase II, which can be used for IHC-Formalin-fixed paraffin-embedded sections,Western blot testing with Human,Mouse samples. anti-topoisomerase I antibody: An autoantibody found in the serum of patients with progressive systemic sclerosis, silicosis, and systemic lupus erythematosus.

[2]. tetrapeptidlänken och topoisomeras-hämmaren DXd [3, 4]. Dosering, förväntad binding site at the GyrA subunit of DNA gyrase and/or the ParC subunit of topoisomerase-IV. Anti-Bacterial Agents Kemiska föreningar.

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Listed below are anti-Topoisomerase II antibodies from multiple suppliers. Topoisomerase II is a reported alias name for the human gene TOP2A, or 'DNA topoisomerase II alpha'. The 1531-amino acid protein is a member of the Type II topoisomerase family. The cellular … Secondary Antibodies.

Anti-Topoisomerase II alpha/TOP2A Antibody

- Find MSDS or SDS, a COA, data sheets and more information. The patients with MPC and PIP joints flexion contractures had higher mean value of anti-topo I abs titers (53.718 ±50.977 vs 8.127 ± 8.915, P < 0.0001) than did those with no contractures.

Diseases with ATA are autoimmune disease because they react with self-proteins. They are also referred to as anti-DNA topoisomerase I antibody (anti-topo I). Se hela listan på sigmaaldrich.com Boster Bio Anti-Topoisomerase (DNA) I, Mitochondrial (TOP1MT) Monoclonal Antibody catalog # M09702. Tested in IHC applications. This antibody reacts with Human.
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Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin, vascular abnormalities and activation of the immune system. The majority of SSc patients have autoantibodies against nuclear antigens. Among these antibodies Anti-topoisomerase I antibodies (also called anti-Scl-70 antibodies) are directed against different epitopes on this enzyme (Simon et al., 2009). Although they are considered highly specific to SSc, recent studies demonstrated the presence of these antibodies in the sera of rare healthy patients as well as patients with systemic lupus erythematosus (SLE) (up to 25%) ( Spencer-Green et al Topoisomerases are enzymes that participate in the overwinding or underwinding of DNA. The winding problem of DNA arises due to the intertwined nature of its double-helical structure.
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Diseases with ATA are autoimmune disease because they react with self-proteins. They are also referred to as anti-DNA topoisomerase I antibody (anti-topo I). 24 antibodies to Topoisomerase I and validated for use in 7 applications (Immunohistochemistry, Western Blot, Immunoprecipitation, Flow Cytometry, ChIP assay, Immunocytochemistry, Immunofluorescence) INTRODUCTION: In the present study, the detection of anti-topoisomerase I (anti-topo I) autoantibodies was evaluated for diagnosis and risk assessment of systemic sclerosis (SSc) patients in a well characterized large monocentric cohort. 2001-10-01 Serum level of anti-topoisomerase I antibodies is in direct relationship with MPC and PIP joints flexion contractures. Key words Systemic sclerosis, anti-topoisomerase I antibody, contracture.

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Anti Cancer properties of TheraCIM®: Antiproliferative activity. Antiangiogenic activity. Pro-apoptotic activity. Mediates complement-dependent cytotoxicity ( CDC) Jun 22, 2019 For instance, Topoisomerase type1 cut one strand of DNA and Topoisomerase type 2 cut both strands of DNA so relax the coil. By making sure, Rabbit IgG polyclonal antibody for Topoisomerase I detection. Tested with WB, Direct ELISA in Human;Mouse;Rat.Hundratusentals antikroppar är tillgängliga Rabbit Polyclonal Topoisomerase II alpha/TOP2A Antibody.